In Southern California, the fires started to spread to Hollywood Hills
Five schools in Los Angeles, California will be closed on Wednesday after two wildfires in the city’s Pacific Palisades area started within a hours of each other on Tuesday night. Over 2 lakh customers in Los ANGELES and Ventura counties are without power. The fires have burned more than 8,500 acres of land in Los Angeles county and over 6,000 acres in Ventura county.
We have to talk about human genome editing
A new study has said that polygenic genome editing ( HPE) could lower the risk of polygenic disease in human embryos. It suggested that HPE could be used to lower the genetic risk of disease by protecting existing combinations of protective variants. It also said that it could be used to prevent normal human ageing and prolonging human life.
A windstorm causes a fire in Southern California
The winds are most common during the cooler months from September to May, Mike Wofford, a lead forecaster at the National Weather Service’s office in California, US, said. The winds are caused by high pressure in the southwestern US that pushes through the mountain passages in Southern California towards a lower pressure area off the coast.
The evaluation and classification of BRCA2 variants is Functional Evaluation and Clinical
Researchers have found that deep learning-derived splice scores can be used to improve genome-wide variant effect predictions using deep learning-Derived Score (CADD-Splice). They also found that the score can be used to generate a risk score that can be used to assess risk of disease. Furthermore, the score can also be used to determine whether patients are candidates for preventive medicine or treatment.
A model of human cell types
We trained a fetal- only GET model with the same peak calling and cell type annotations as Domcke et al.1 model. The data augmentation improves the diversity of inputs and improves the model for data from a single cell type. We identified target genes for each TF within predefined motifs and computed the mean expression levels of both the target genes and the corresponding TFs.
The X-ification of Meta is related to X-ification
Facebook CEO Mark Zuckerberg said Meta, the platform that enables fact-checking of news, will be shut down “in the near future”. The social media platform had partnered with fact-checking organisations and newsrooms across the globe to tackle fake news. Meta’s global policy chief Joel Kaplan had said the platform has decided to stop collaborating with fact-checking organisations.
The Justice Department wants to make public only parts of their report on the Trump cases
US Special Counsel Jack Smith has asked the Department of Justice to release his report on President-elect Donald Trump’s mishandling of classified documents by January 20. Smith had earlier dismissed the case against Trump, who is accused of illegally leaking classified documents to supporters after his election victory. However, the special counsel has been asked to submit his final report to the Attorney General.
The development of quantum mechanics was a few months ago
The UN has declared 2025 to be the International Year of Quantum Science and Technology, which commemorates the first 100 years of the improvement of the standard model and the modern-day Evolution of the Quantum World. The first applications of Heisenberg’s quantum-mechanical theory had been worked on by Lucy Mensing, a member of his group.
Police say that the man who blew up Cybertruck in Las Vegas used online planning tools
Matthew Livelsberger, the soldier who blew up his vehicle outside the Trump International Hotel in Las Vegas on New Year’s Day, had a “possible manifesto” on his mobile phone, police said. Livelsberger had a “possible manifesto” and sent an email to a podcaster, they added. Police further said that Livelsberger had used generative AI to plan the attack.
Meta users are not being left to wade through hate and misinformation
Meta has completely rolled back the fact-checking policies that were put in place after it was revealed that the tech platform was involved in influence operations that were designed to influence elections and promote violence. Meta’s chief global affairs officer said the decision was made to allow more topics to be discussed on the company’s platforms.